The COVID-19 global health emergency has greatly impacted the educational field. Faced with unprecedented stress situations, professors, students, and families have employed various coping and resilience strategies throughout the confinement period. High and persistent stress levels are associated with other pathologies; hence, their detection and prevention are needed. Consequently, this study aimed to design a predictive model of stress in the educational field based on artificial intelligence that included certain sociodemographic variables, coping strategies, and resilience capacity, and to study the (...) relationship between them. The non-probabilistic snowball sampling method was used, involving 337 people from the university education community in south-eastern Spain. The Perceived Stress Scale, Stress Management Questionnaire, and Brief Resilience Scale were administered. The Statistical Package for the Social Sciences was used to design the architecture of artificial neural networks. The results found that stress levels could be predicted by the synaptic weights of coping strategies and timing of the epidemic, with a predictive capacity of over 80% found in the neural network model. Additionally, direct and significant associations were identified between the use of certain coping strategies, stress levels, and resilience. The conclusions of this research are essential for effective stress detection, and therefore, early intervention in the field of educational psychology, by discussing the influence of resilience or lack thereof on the prediction of stress levels. Identifying the variables that maintain a greater predictive power in stress levels is an effective strategy to design more adjusted prevention programs and to anticipate the needs of the community. (shrink)

BackgroundResearch during 2020 has been rapidly attending to the impact of COVID-19 on various dimensions of wellbeing on adults and children around the world. However, less attention has focused on the psychoeducational impact on children and their families. To our knowledge, no currently available studies have looked specifically at the impact of COVID-19 on students with dyslexia and their families. Research on this topic is needed to offer greater support for this population of students and their families.ObjectiveThe main objective of (...) this paper is to examine the psychoeducational impact of the required COVID-19 quarantine in Spain among children with dyslexia and their families.MethodA sample of 32 children with dyslexia and their mothers participated in this study.MeasuresChildren and adolescents with dyslexia and their mother completed several measures before the required national quarantine in Spain and again during the quarantine. Children completed measures of depression, state anxiety, reading activity, and reading motivation. Mothers provided demographic information and completed measures related to students’ emotional and behavioral difficulties as well as parenting stress, parental distress, and a questionnaire about educational problems during quarantine.ResultsMajor findings showed that during quarantine, children with dyslexia had increased levels of depression and anxiety symptoms, and parents perceived their children as having more emotional symptoms, hyperactivity-inattention, and conduct problems. During quarantine, children and adolescents with dyslexia also showed less reading activity and less reading motivation. Parents also reported significantly more stress, during quarantine compared to pre-quarantine conditions. Some demographic and psychological variables predicted children’s state anxiety as well parental stress. The questionnaire related to impacts of quarantine also revealed several important findings. For example, nearly all parents of children with dyslexia reported difficulties in establishing study routines, that the quarantine negatively affected their child’s learning, and that they did not receive sufficient help from teachers on how to support their child’s learning. Additionally, the vast majority of the parents were very worried about the child’s learning and school success, the child’s motivation and interest in reading, the child’s peer relations, and the professional skills of the child’s teacher.ConclusionThis study offers a preliminary investigation into this topic and elucidates several psychoeducational challenges that children with dyslexia and their families have experienced during the quarantine in Spain. Study findings highlight the need to provide immediate support for children with dyslexia and emphasizes the importance of developing prevention programs to mitigate any future negative impacts of COVID-19 on children with dyslexia and their parents. (shrink)

Rare neuromuscular diseases are a group of pathologies characterized by a progressive loss of muscular strength, atrophy, fatigue, and other muscle-related symptoms, which affect quality of life levels. The low prevalence, high geographical dispersion and disability of these individuals involve difficulties in accessing health and social care services. Teleassistance is presented as a useful tool to perform psychosocial interventions in these situations. The main aim of this research is to assess the effects of a teleassistance psychosocial program on the QoL (...) levels of people with RNMDs who have different levels of disability. A sample of 73 participants was divided into an experimental group, which participated in the intervention, and a control wait list group. QoL was evaluated through the SIP and the SF-36, and disability through the WHO-DAS II. The participants with a moderate to severe level of disability were those who most benefited from the intervention. The results also revealed that the psychosocial teleassistance program was suitable to improve physical and psychosocial aspects of people suffering from a rare neuromuscular disease with a moderate level of disability, but just psychosocial aspects in those with a severe level of disability. (shrink)

Artificial intelligence is a useful predictive tool for a wide variety of fields of knowledge. Despite this, the educational field is still an environment that lacks a variety of studies that use this type of predictive tools. In parallel, it is postulated that the levels of self-esteem in the university environment may be related to the strategies implemented to solve problems. For these reasons, the aim of this study was to analyze the levels of self-esteem presented by teaching staff and (...) students at university and to design an algorithm capable of predicting these levels on the basis of their coping strategies, resilience, and sociodemographic variables. For this purpose, the Rosenberg Self-Esteem Scale, the Perceived Stress Scale, and the Brief Resilience Scale were administered. The results showed a relevant role of resilience and stress perceived in predicting participants’ self-esteem levels. The findings highlight the usefulness of artificial neural networks for predicting psychological variables in education. (shrink)

Localization Wireless Sensor Networks (WSN) represent a research topic with increasing interest due to their numerous applications. However, the viability of these systems is compromised by the attained localization uncertainties once implemented, since the network performance is highly dependent on the sensors location. The Node Location Problem (NLP) aims to obtain the optimal distribution of sensors for a particular environment, a problem already categorized as NP-Hard. Furthermore, localization WSN usually perform a sensor selection for determining which nodes are to be (...) utilized for maximizing the achieved accuracy. This problem, defined as the Sensor Selection Problem (SSP), has also been categorized as NP-Hard. While different metaheuristics have been proposed for attaining a near optimal solution in both problems, no approach has considered the two problems simultaneously, thus resulting in suboptimal solutions since the SSP is biased by the actual node distribution once deployed. In this paper, a combined approach of both problems simultaneously is proposed, thus considering the SSP within the NLP. Furthermore, a novel metaheuristic combining the Black Widow Optimization (BWO) algorithm and the Variable Neighbourhood Descent Chains (VND-Chains) local search, denominated as BWO-VND-Chains, is particularly devised for the first time in the author’s best knowledge for the NLP, resulting in a more efficient and robust optimization technique. Finally, a comparison of different metaheuristic algorithms is proposed over an actual urban scenario, considering different sensor selection criteria in order to attain the best methodology and selection technique. Results show that the newly devised algorithm with the SSP criteria optimization achieves mean localization uncertainties up to 19.66 % lower than traditional methodologies. (shrink)

Patina is the word used for the green or brown film formed on the surface of old bronze, an excess of which can mask the true characteristics of the original masterpiece. Filippo Baldinucci used the word patina in a modern sense for first time in his book “Tuscan Vocabulary of the Art of Design”. Metaphors have been part of philosophical speech since the time of Plato. This figure of speech is used to attempt to provide a sensitive presence of an (...) idea to improve understanding and to make a more vivid perception of that concept. On analysing the creative process of contemporary re-search on health topics and its further dissemination, we defend the epistemological thesis that there is always some degree of patina on an original article and this may obscure the underlying scientific work. Conclusion: We consider that patina in scientific papers is very different from the concept of epidemiological bias. We think that any researcher who reads an original article acts as a restorer of knowledge. If a reader is aware of the existence of scientific patina, that reader will know how to look through it and see the masterpiece hidden underneath. (shrink)

El objetivo de este artículo es mostrar cómo la imagen que dio Manuel Chaves Nogales de la revolución rusa a través de sus artículos en los años treinta, siendo vanguardia del periodismo de entonces, tuvo un sentido histórico. La hipótesis es que el periodismo, informando sobre el presente, puede aportar a los historiadores alguna lección. Para mostrar la conciencia histórica del periodismo de Chaves Nogales se contextualiza al autor entre otros viajeros de la época a la Unión Soviética, se (...) analiza la manera en la que Chaves interpreta las huellas de la revolución en las personas y en su entorno y se relaciona con la microhistoria. (shrink)

I deal here with one of Boghossian’s arguments against content externalism, related to ourinferential rationality(to use his term). According to his reasoning, the apriority of our logical abilities is inconsistent with certain externalist assumptions. Nevertheless, the problem constitutes an important challenge foranytheory of content, not just for externalism. Furthermore, when we examine what internalists may propose to solve the problem, we see that externalists have at their disposal a more promising repertoire of possible replies than internalists. In that sense, insofar (...) as Boghossian’s scenario is relevant to the debate externalism/internalism, it can be seen (against Boghossian’s original intention) as providing additional evidence for content externalism. (shrink)

Necessitism about individuals claims that necessarily every individual necessarily exists. An analogous necessitist thesis attributes necessary existence to properties and relations. Both theses have been defended by Williamson. Furthermore, Williamson specifically argues against the hybrid conjunction of first-order contingentism and higher-order necessitism; a combination that would bring about additional drawbacks. I work out a defence of the hybrid combination, including some replies to Williamson’s additional objections. Considerations of ontological parsimony and pre-theoretical intuitions favour the hybrid view over necessitism at all (...) orders. (shrink)

Hume argued that inductive inferences do not have rational justification. My aim is to reject Hume’s argument. The discussion is partly motivated by an analogy with Carroll’s Paradox, which concerns deductive inferences. A first radically externalist reply to Hume (defended by Dauer and Van Cleve) is that justified inductive inferences do not require the subject to know that nature is uniform, though the uniformity of nature is a necessary condition for having the justification. But then the subject does not have (...) reasons for believing what she believes. I defend a moderate externalist account that seeks to partly accommodate that objection to the radical externalist proposal. It is based on an extension of Peacocke’s theory of concepts: possession conditions for predicative concepts standing for natural properties include (fallible) dispositions to project them to new cases in accordance with inductive inferential patterns. (shrink)

A common view about Moore’s Proof of an External World is that the argument fails because anyone who had doubts about its conclusion could not use the argument to rationally overcome those doubts. I agree that Moore’s Proof is—in that sense—dialectically ineffective at convincing an opponent or a doubter, but I defend that the argument (even when individuated taking into consideration the purpose of Moore’s arguing and, consequently, the preferred addressee of the Proof) does not fail. The key to my (...) defence is to conceive the Proof as addressed to subjects with a different epistemic condition. To sustain this view I formulate some hypothesis about the common general purpose of arguing and I defend that it can be fulfilled even when the addressee of an argument is not someone who disbelieves or doubts its conclusion. (shrink)

Según Williamson, saber y creer son estados mentales, pero creer algo verdadero y creer justificadamente algo verdadero no lo son. Ese tratamiento discriminatorio es relevante para la epistemología de Williamson. Su principal tesis epistemológica negativa y su principal tesis epistemológica positiva están en peligro si su teoría metafísica sobre lo mental es incorrecta. Presento aquí un problema para dicha teoría: impone limitaciones implausibles a los posibles usos de conceptos y expresiones lingüísticas. Describiré algunas opciones que tendría Williamson para evitar el (...) problema; pero sostendré que acarrean cierta dosis de arbitrariedad. (shrink)

I present an epistemological puzzle about perceptual knowledge and its relation to the evaluation of probabilities. It involves cases, concerning a given subject S and a proposition P in a determinate context, where apparently: S has perceptual knowledge of P; the epistemic justification S has for believing Not-P is much greater than her epistemic justification for believing P. If those two theses were true, the following very plausible epistemological principle would fail: If S knows P, then the epistemic justification S (...) has for believing Not-P is not greater than her epistemic justification for believing P. I offer a solution to the puzzle, which is compatible with basic intuitions and theses of orthodox Bayesianism. (shrink)

Timothy Williamson has defended the claim that any philosophically satisfying conception of modality that encompasses possible worlds semantics (PWS) commits us to the Barcan Formula. His argument depends on the assumption that the domain of what there is (the domain of the actual world) has to be identified with the domain D(@), where @ is the index or possible world that in PWS represents , or stands for , the actual world. I work out an interpretation of the relation between (...) PWS and possible worlds terminology that makes it plausible to reject that assumption. (shrink)

E. Machery and some collaborators have used survey data to criticize Kripke’s anti-descriptivism about proper names. I highlight a number of drawbacks in the tests of Machery et al. Some of my objections concern their ambiguity. In particular, the responses that–according to them–reveal descriptivist intuitions can be interpreted as anti-descriptivist responses. Furthermore, their vignettes are inconsistent. I also discuss other issues related to the role of intuitions in philosophy; Machery et al.’s theses depends on an unjustified assumption: there is not (...) expertise regarding intuitions. (shrink)

Tanto la Fórmula Barcan como la postulación de possibilia contradicen los juicios intuitivos preteóricos de la mayoría de los sujetos, favorables al actualismo sobre la naturaleza de los mundos posibles. En este artículo discuto y rechazo dos argumentos que pretenderían contrarrestar tales juicios, y que conciben erróneamente la relación entre la semántica de mundos posibles y nuestros lenguajes naturales modales. El argumento más importante asume que el dominio de todas las entidades es idéntico al dominio de @. Desarrollo una interpretación (...) de la SMP conforme a la cual esa tesis no está suficientemente justificada. /// Barcan Formula and the postulation of possibilia contradict the pretheoretical intuitive judgments of most people, which favour actualism about possible worlds. In this paper I discuss and reject two arguments against such judgments, both of which conceive wrongly the relation between possible worlds semantics and modal natural languages. The more important argument assumes that the domain of the actual world is identical to the domain of @. I develop an interpretation of PWS which elucidates why that thesis is unwarranted. (shrink)

Kripke formula cuatro objeciones en contra de una solución disposicionalista simple al enigma wittgensteiniano sobre seguir una regla. En este trabajo presento dos propuestas parcialmente disposicionalistas diferentes a la teoría disposicionalista simple que Kripke discute y defiendo que aquellas cuatro objeciones no les afectan. Una de esas dos propuestas puede atribuirse, con cierta precaución, al propio Wittgenstein. La otra, que me parece preferible, invoca una noción teleológica de disposición. Ambas propuestas apelan al concepto de simplicidad, o —alternativamente— al concepto de (...) similitud natural. Rechazo también ciertas críticas que Kripke hace del uso de tales conceptos para solucionar el enigma sobre seguir una regla. (shrink)

En este artículo discuto el supuesto compromiso de la lógica modal cuantificada con el esencialismo. Entre otros argumentos, Quine, el más emblemático de los críticos de la modalidad, ha objetado a la lógica modal cuantificada que ésta se compromete con una doctrina filosófica usualmente considerada sospechosa, el esencialismo: la concepción que distingue, de entre los atributos de una cosa, aquellos que le son esenciales de otros poseidos sólo contingentemente. Examino en qué medida Quine puede tener razón sobre ese punto explorando (...) una analogía entre la lógica modal y la logica clásica de primer orden. Con ello se pretende proporcionar una visión clarificadora sobre el estatus de la lógica modal y su relación con la lógica en general.In this paper I discuss the alleged commitment of quantified modal logic to philosophical essentialism. Besides some other more or less related arguments against quantified modal logic, Quine (its more prominent critic) objects to it by claiming its commitment to a philosophical doctrine usually regarded as suspicious, essentialism: the view that some of the attributes of a thing are essential to it, and others are accidental. I study to what extent Quine can be right about this specific issue. I defend some of his views by exploring an analogy between modal logic and standard first order logic. That serves to get a better understanding of the status of modal logic and its relation with logic in general. (shrink)

Kripke argued for the existence of necessary a posteriori truths and offered different accounts of why certain necessary truths seem to be contingent. One of these accounts was used by Kripke in an argument against the psychophysical identity thesis. I defend the claim that the explanatory force of Kripke's standard account of the appearance of contingency relies on the explanatory force of one of the more general accounts he also offers. But the more general account cannot be used to undermine (...) the psychophysical identity thesis. Specifically, a crucial feature in Kripke's standard account, which is needed to argue for dualism, is explanatorily superfluous. Alternative accounts that are similar to Kripke's original one but lack that trait would also explain the phenomenon. Consequently, the Kripkean dualist argument is blocked. /// Kripke ha argumentado que existen verdades necesarias a posteriori, y ha ofrecido diferentes explicaciones de por qué ciertas verdades necesarias parecen contingentes. Una de esas explicaciones se usaba en un argumento con el que Kripke criticaba la tesis de la identidad psicofísica. En este trabajo sostengo que la fuerza explicativa de la explicacion kripkeana estándar de la apariencia de contingencia depende de la fuerza explicativa de una de las otras explicaciones que Kripke también propone. Pero esa otra explicación, más general, no sirve para rechazar la identidad psicofísica. Con-cretamente, un rasgo crucial de la explicación kripkeana estandar resulta explicativamente superfluo. Explicaciones alternativas, similares a la de Kripke pero que carezcan de ese rasgo, explicarían también el fenómeno. Como consecuencia, el argumento dualista kripkeano queda bloqueado. (shrink)

I present some puzzling cases regarding knowledge and its relation to rational credence. They seem to entail a failure of an apparently correct principle: if S knows P, then the epistemic justi...

Kripke argued for the existence of necessary a posteriori truths, and tried to explain why some of them seem to be contingent. His main explanation motivated two philosophical proposals: the attempt - linked to some interpretations of two-dimensionalism - to analyse the epistemic concept of a priori truth using metaphysical modal concepts; the argument for psychophysical dualism worked out by Kripke relying on his explanation of the appearances of contingency. I point out several difficulties for , and argue that can (...) oe blocked because of the existence of alternative accounts of the phenomenon. (shrink)

EI debate entre la concepción descriptivista de los nombres propios y la teoría de la referencia directa concierne -principalmente- a esta cuestión: (es la función referencial de los nombres propios reduciblemediante la función descriptiva y las funciones logicas? Una tesis distintiva central de Kripke es 10 que denominamos particularismo semántico modal: la función referencial es irredueible, incluso cuando los nombre propios aparecen en enunciados modales. Se presenta aquí una exégesis de las críticas de Kripke contra cierta interpretacion metafóriea de los (...) mundos posibles (que los considera como Iugares lejanos observados con telescopios) interpretándolas como elementos cruciales en su defensa del particularismo semántieo modal.Tbe debate between the description theory of proper names and direct reference is -mainly- a debale on whether or not the referential function of proper names is reducible in term of descriptive and logical functions. A central distinctive thesis in Kripke’s work is what I call modal semantic particularism: the referential function is irreducible even when proper names appear in modal contexts. I present all exegesis of Kripke’s comments against a certain metaphorical understanding of possible worlds (as distant countries discovered through teleseopes) according to which these comments are crucial claims in hisdefense of modal semantic particularism. (shrink)

En el contexto de este artículo denominaremos mentalismo a la conjunción de dos tesis diferentes: (i) para que las expresiones lingüísticas tengan significado es necesario que haya entidades de carácter mental; (ii) tales entidades mentales son suficientes para fijar el significado de las expresiones correspondientes (es decir, lo determinan). Es característico deI segundo Wittgenstein el rechazo a ambas tesis. Pero son sus argumentos contra (ii), especialmente a partir de las consideraciones sobre seguir una regla, los que han concentrado casi toda (...) la atención. En este trabajo presento el argumento principal de Wittgentein contra (i), diferenciándolo de sus objeciones a (ii).In this article mentalism will be used to denominate the conjunction of two thesis: (i) it is a necessary condition for linguistic expressions having meaning the existence of mental entities; (ii) these mental entities are sufficient to fix the meaning of the corresponding expressions (they determine it). The two thesis are rejected by the later Wittgenstein. Most of the attention, though, has been paid to his arguments against (ii), especially based on discussions of rule-following. In this paper I work out Wittgenstein’s main argument against (i), and I distinguish it from his objections to (ii). (shrink)

En este artículo presento, clarifico y exploro algunas virtudes potenciales de una determinada teoría —de carácter intencionalista— sobre lo cómico. Su tesis mínima principal establece una condición necesaria para la comicidad: quien evalúaaprecia una situación como humorística/cómica reconoce un perjuicio o daño ocasionado a ciertos sujetos intencionales. Una versión más fuerte establece que la comicidad deriva de dicho perjuicio. El perjuicio es aquello que, cuando se combina con otros factores, encontramos humorístico/cómico. Clarificar la teoría conlleva una tarea de comparación con (...) otras concepciones del humor, en particular, con la teoría de la incongruencia. (shrink)

This work addresses the objections to analyticity and meaning atribution to single sentences included in Quines Two Dogmas of Empiricism. First, an interpretation of Two Dogmas is provided which implies that the strongest argument against the analytic/synthetic distinction is based on epistemic holism. Then, two possible rejoinders to Quine are presented. They rely on the following thesis: (i) semantic holism that follows from the conjunction of Quines epistemic holism and verificationism is compatible with assignation of meaning to single sentences, which (...) in turn paves the way for a characterization of analyticity; (ii) epistemic holism and the related thesis that every true sentence is empirically revisable are objectionable if we accept criteria of individuation for truth bearers different from those assumed by Quine. (shrink)

Presento y defiendo dos reinterpretaciones de la prueba ideada por Putnam para demostrar que no somos cerebros en una cubeta. Ambas resaltan explícitamente el papel desempeñado por el autoconocimiento de nuestros propios pensamientos y por el externismo sobre el contenido. La primera asume que el externismo implica que un cerebro en una cubeta no puede pensar el contenido proposicional relevante (constituido por conceptos acerca de cerebros y cubetas). La otra versión invoca una tesis externista más débil, conforme a la cual (...) un sujeto corpóreo y un cerebro en una cubeta no pueden compartir el contenido proposicional relevante. (shrink)

Williamson defiende la regla del conocimiento, RK, sobre las aseveraciones: debemos aseverar que p sólo si sabemos que p. En este trabajo exploro algunas consecuencias interesantes de RK: (a) en ocasiones, al hacer una aseveración correcta transmitimos (como implicatura) un significado no literal verdadero, que \sin embargo\ no podría ser correctamente aseverado; (b) ese tipo de implicatura se da, entre otros casos, en una cierta subclase de las implicaturas: las implicaturas argumentativas; (c) RK y la noción de implicatura argumentativa permiten (...) explicar la tendencia a tratar de forma equivalente diferentes tipos de argumentos antiescépticos inspirados en Moore.Williamson defends the knowledge rule, KR, about assertions: one must: assert p only if one knows p. In this work I explore some interesting consequences of KR: (a) sometimes, when making a correct assertion we transmit (as an implicature) a true non-literal meaning which \nevertheless\ could not be rightly asserted; (b) this kind of implicatures are present, for instance, in a certain subclass of implicatures: argumentative implicatures; (c) KR and the notion of argumentative implicature allow for an explanation of the tendency to treat different kinds of Moore-like antiskeptical arguments as if they were equivalent. (shrink)

Igor Douven has offered an original reconstruction and defence of Putnam's model-theoretic argument against metaphysical realism. Douven's construal has notable exegetical virtues, since it makes sense of some assumptions in Putnam's argument which his opponents have considered question-begging or puzzling. In this article I provide an indirect defence of metaphysical realism, by showing why this new version of the anti-realist argument should also be rejected. The main problems in the Douven-Putnam argument come from ascribing to the realist a distorted view (...) of correspondence truth. The view entails that when no feature selects just one of all the possible interpretations of language the existence of an interpretation suffices to make true a theory. The sensible realist is not committed to this extreme conception of correspondence truth. /// Igor Douven ha presentado y defendido una reconstructión del argumento teórico-modelista de Putnam contra el realismo metafísico. Esta versión tiene ciertas virtudes exegéticas, pues hace inteligible algunos presu- puestos putnamianos que sus críticos han considerado injustificados o sorprendentes. En este artículo proporciono una defensa indirecta del realismo metafisico, mostrando por qué debe también rechazarse el argumento antirrealista bajo esta nueva forma. Los problemas principales del argumento Douven-Putnam proceden de atribuir al realista una concepción distorsionada de la idea de verdad como correspondencia. Conforme a esa concepción, la ausencia de factores que seleccionen una única interpretación del lenguaje de entre las muchas posibles conlleva que la existencia de alguna interpretación ya es suficiente para hacer verdadera a una teoría que sea consistente. El realista sensato no está obligado a aceptar esa tesis. (shrink)

Since the realisation that the antigen‐binding regions of antibodies, the variable (V) regions, can be uncoupled from the rest of the molecule to create fragments that recognise and abrogate particular protein functions in cells, the use of antibody fragments inside cells has become an important tool in bioscience. Diverse libraries of antibody fragments plus in vivo screening can be used to isolate single chain variable fragments comprising VH and VL segments or single V‐region domains. Some of these are interfering antibody (...) fragments that compete with protein‐protein interactions, providing lead molecules for drug interactions that until now have been considered difficult or undruggable. It may be possible to deliver or express antibody fragments in target cells as macrodrugs per se. In future incarnations of intracellular antibodies, however, the structural information of the interaction interface of target and antibody fragment should facilitate development of binding site mimics as small drug‐like molecules. This is a new dawn for intracellular antibody fragments both as macrodrugs and as precursors of drugs to treat human diseases and should finally lead to the removal of the epithet of the ‘undruggable’ protein‐protein interactions. (shrink)